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. Author manuscript; available in PMC: 2010 Jun 24.
Published in final edited form as: Mech Dev. 2008 Dec 11;126(3-4):117–127. doi: 10.1016/j.mod.2008.11.008

Fig. 3.

Fig. 3

Body wall closure defects in Bmp2 heterozygotes and Bmp2−/+; Bmp4lacZ/+ compound mutants. (A and B) Alcian Blue and Alizarin Red-stained skeletons from adult mice show split xiphoid processes in Bmp2−/+ (asterisk), but not wild type mice. (C and D) Hematoxylin and eosin stained cross sections through the thoracic cavity of E15.5 embryos. Arrowheads indicate lateral edges of the ventral body wall of a Bmp2−/+; Bmp4lacZ/+ mutant which have failed to fuse, leading to externalization of the heart (arrow) and other organs.