Fig. 8.
Neural crest cells are formed in the mutant but display impaired migration. (A–C) In situ hybridization of embryos at E8.75 (A) and E9.5 (B–C) using a Sox10 probe. i, neural crest cells migrating into the first branchial arch; ii, neural crest cells migrating into the second branchial arch. (D–E) Sections through the cranial regions of E8.5 (D) and E9.5 (E) embryos hybridized with a Sox10 probe, with planes of cleavage indicated in panel A–C.