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. 2000 Feb 15;105(4):459–468. doi: 10.1172/JCI8185

Figure 6.

Figure 6

Flow cytometric profiles of thymocytes and splenocytes from 4.1-NOD and 4.1-NOD.lpr+/+ mice. CD4, CD8, and Vβ11 profiles of thymocytes (a) and splenic cells (b) from 4.1-NOD and 4.1-NOD.lpr+/+ mice (n = 4–8 mice/group, 8–14 weeks old). Upper panels show CD4 vs. CD8 contour plots of cells stained with anti-CD8–PE, anti-Vβ11–FITC, and anti-CD4–biotin plus streptavidin-PerCP. The lower panels show the Vβ11 fluorescence histograms of each T-cell subset after electronic gating. Numbers indicate the average percentage of cells (upper panels) or number of Vβ11+ cells (lower panels) in each subset. DP, double-positive cells; DN, double-negative cells.