Table 3.
MIC and IC50 values of active plant extracts with respect to M. smegmatis and clinically-relevant bacterial species.
| Plant | Part | M. smegmatis | M. bovis | M. tuberculosis | S. aureus | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| mg/ml | mg/ml | mg/ml | mg/ml | ||||||||||
| MIC | IC50 | MIC | IC50 | MIC | IC50 | MIC | IC50 | ||||||
| L. novae-zelandiae | Bark | 0.04 | 0.02 ± 0.01 | 1.50 | 0.54 ± 0.03 | 4.16 | 2.39 ± 0.33 | > 10 | > 10 | ||||
| Cambium | 0.50 | 0.25 ± 0.01 | 2.50 | 1.63 ± 0.21 | 3.75 | 1.86 ± 0.22 | > 10 | > 10 | |||||
| L. bullata | Leaf | 1.00 | 0.31 ± 0.15 | 3.12 | 2.59 ± 0.43 | 6.51 | 5.59 ± 0.32 | > 10 | > 10 | ||||
| M. excelsa | Leaf | 0.63 | 0.11 ± 0.06 | 8.35 | 6.95 ± 3.07 | > 10 | 4.83 ± 0.43 | 2.20 | 1.17 ± 0.39 | ||||
| Flower | 0.63 | 0.41 ± 0.06 | 3.13 | 1.12 ± 0.12 | 4.18 | 2.19 ± 0.76 | > 10 | > 10 | |||||
| M. laetum | Leaf | 0.63 | 0.34 ± 0.02 | > 10 | > 10 | > 10 | > 10 | > 10 | > 10 | ||||
| P. tenuifolium | Leaf | 2.00 | 0.78 ± 0.34 | > 10 | 5.37 ± 1.35 | 1.25 | 0.51 ± 0.11 | > 10 | > 10 | ||||
| P. crassifolius | Leaf | 0.63 | 0.31 ± 0.01 | 6.25 | 4.08 ± 1.76 | 3.58 | 1.74 ± 0.18 | > 10 | > 10 | ||||
MIC, minimum inhibitory concentration. IC50, 50% inhibitory concentration.