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Comparison of PTX with other microtubule-active drugs. HCT116 cells (a) or p21–/– cells (b) were pretreated with 100 ng/mL doxorubicin or left without pretreatment. After 16 hours, cells were treated with 100 ng/mL of indicated drug. MTT assay was performed after 2 days. Results represent percent of untreated cells or DOX-pretreated cells, respectively. Epo, epothilone. VBL, vinblastine.
