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. 2000 Feb 15;105(4):533–539. doi: 10.1172/JCI8625

Figure 5.

Figure 5

Protection by p21 against PTX in p21–/–. (a) Cells were infected with 10 moi Ad-p21, and after 24 hours, treated with 100 ng/mL PTX for 20 hours as indicated. Cells were lysed, and immunoblot for p53 and p21 was performed. (b) Cells were infected with 10 moi Ad-p21, and after 24 hours, cell-cycle analysis was performed. No doxorubicin or paclitaxel was added in this experiment. (c). Cells were infected with 10 moi Ad-p21, and after 24 hours, treated with 100 ng/mL PTX as indicated. MTT assays were performed after 2 days.