Skip to main content
. Author manuscript; available in PMC: 2012 Jul 1.
Published in final edited form as: Int J Biochem Cell Biol. 2010 Jan 12;43(7):1059–1064. doi: 10.1016/j.biocel.2009.12.022

Table 1.

Effects of resveratrol on CSE-stimulated caspase activity

Cas 9 Without DTT
With DTT
4h 24h 4h 24h
0 1±0.05 1.23±0.19 1.55±0.08 1.55±0.23
R 0.82±0.13 1.46±0.21 1.46±0.09 2.24±0.33
10% 1.77±0.15* 3.23±0.32* 4.1±0.33* 5.04±0.42*
10%+R 2.31±0.25*# 4.26±0.28*# 4.99±0.29*# 6.1±0.35*#
20% 3.87±0.42* 5.74±0.42* 6.29±0.52* 8.33±0.31*
20%+R 5.21±0.38*# 7.25±0.58*# 8.64±0.46*# 9.51±0.49*#
Cas 3
0 1±0.05 1.04±0.23 1.74±0.09 2.25±0.31
R 0.81±0.07 1.72±0.37 1.61±0.06 2.42±0.16
10% 1.88±0.21* 23.13±3.6* 5.76±0.8* 44.21±5.18*
10%+R 2.61±0.3*# 41.39±5.71*# 8.12±0.71*# 58.81±4.32*#
20% 4.23±0.59* 34.63±3.42* 7.26±0.77* 52.88±6.71*
20%+R 5.69±0.42*# 53.24±8.69*# 9.97±1.26*# 78.17±5.25*#

HBE1 cells were pretreated with 5 μM resveratrol for 24 h before being treated with/without CSE for 4 and 24 h; and the caspase activity was measured as described in Methods. Values are mean ± SE of three experiments.

*

P<0.05 compared with vehicle control (ethanol) of 0% CSE treatment;

#

P<0.05 compared with vehicle control (ethanol) of same CSE exposure. Cas 3, caspase 3; cas 9, caspase 9; R, resveratrol; 0, vehicle control (ethanol).