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. 2010 May 19;9:19. doi: 10.1186/1475-2840-9-19

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Copyright ©2010 Lu et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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The dose-response relation of circumferential tension for the various groups. A: Effect of age (11 weeks and 19 weeks) on vasoconstriction. B: Effects of Rosi treatment on vasoconstriction. Lean: Zucker lean rats. ZDF: ZDF rats. Rosi: rosiglitazone treatment. 11w: 11 weeks of age. 19w: 19 weeks of age. #: ANOVA indicates significant difference (p < 0.05) of the dose-response curve between the ZDF rats at different age and lean rats. *: Statistical difference (p < 0.05) at single dose between ZDF rats at different age and lean rats.