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Effect of native CTLA4-Ig or Y100F-Ig treatment on the numbers of (a) T cells and (b) macrophages, per 50 glomerular sections, detected by immunohistology of kidney tissue in groups of WKY rats (n = 5–8) with EAG. Results shown represent the mean ± SD of each group at week 4 after immunization. (*P < 0.001, positive control vs. CTLA4-treated and Y100F-treated groups).
