Skip to main content
. 2010 Jan 29;25(7):2178–2187. doi: 10.1093/ndt/gfp765

Table 2.

Serum creatinine, urinary creatinine and GFR

Men n = 355 Women n = 589 All n = 944 Men vs. women P values
Serum creatinine (μmol/l) 89.7 (18.3) 72.5 (13.3) 79.0 (17.4) <0.001
24-hour urinary creatinine (mmol) 9.8 (2.7) 7.6 (2.0) 8.4 (2.6) <0.001
Creatinine clearance 82.3 (22.4) 85.3 (22.7) 84.1 (22.6) 0.051
Estimated GFR (ml/min/1.73 m2)
 Cockcroft–Gault 72.1 (15.6) 76.2 (20.0) 74.7 (18.6) 0.001
 MDRD-4 104.7 (23.0) 100.9 (22.6) 102.3 (22.8) 0.014
 MDRD-4 without correction for race 86.5 (19.0) 83.4 (18.6) 84.6 (18.8) 0.014
 CKD-EPI 103.6 (18.2) 102.8 (19.0) 103.1 (18.7) 0.52
 CKD-EPI without correction for race 89.6 (15.8) 89.2 (16.5) 89.4 (16.2) 0.73
Limits of agreement
Estimated GFR minus creatinine clearance (ml/min/1.73 m2)
 Cockcroft–Gault −10.1 (−44.8 to 24.5) −9.0 (−44.6 to 26.6) −9.4 (−44.7 to 25.8) 0.36
 MDRD-4 22.4 (−22.1 to 66.8) 15.6 (−23.6 to 54.8) 18.2 (−23.6 to 59.9) <0.001
 MDRD-4 without correction for race 4.2 (−36.7 to 45.1) −1.9 (−38.4 to 34.6) 0.4 (−38.2 to 39.0) <0.001
 CKD-EPI 21.3 (−17.4 to 60.0) 17.6 (−17.2 to 52.4) 19.0 (−17.9 to 53.8) 0.003
 CKD-EPI without correction for race 7.3 (−30.2 to 44.8) 4.0 (−30.0 to 37.9) 5.2 (−30.2 to 40.7) 0.006

Means ± SD except for estimated GFR minus creatinine clearance where mean differences and limits of agreement are given.