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. 2010 Feb 1;25(7):2107–2119. doi: 10.1093/ndt/gfq006

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© The Author 2010. Published by Oxford University Press [on behalf of the ERA-EDTA]. All rights reserved. This is an Open Access article of the Creative Commons Attribution License (http://creativecommons.org/licenses?by-nc/2.0/uk) which permits unres distribution, and reproduction in any medium, provided the original work is properly cited.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5),which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 5 — Localization of claudin-3, -4 and -8 compared to THP: photomicrographs showing serial sections of human renal cortical tissue stained for L. tetragonolobus (A), claudin-8 (B), claudin-4 (C), THP (D), claudin-3 (E) and EMA (F) [claudin-8, -4 and -3 stained tubules that were coincident with similar ones that were positive for EMA and negative for L. tetragonolobus (asterisks in A–C, E and F), confirming the expression of these claudins in the distal nephron (TAL or DCT) or collecting duct; THP staining was coincident with a subpopulation of EMA positive tubules that was positive for claudin-3 and not claudin-4 or -8 or L. tetragonolobus, indicating that claudin-3 is expressed in the TAL (arrows and arrowheads in A–F); scale bar 100 µm].