Fig. 9.

Localization of claudin-1: photomicrographs showing serial sections of human renal cortical tissue stained for ZO-1 (A), calbindin (B), aquaporin-2 (C), claudin-1 (D), THP (E) and L. tetragonolobus (F) [claudin-1-, calbindin- and aquaporin-2-stained coincident tubules that were negative for THP and L. tetragonolobus (arrowheads in B–F); there were some calbindin positive tubules that were negative for claudin-1, THP and aquaporin-2 (asterisks in B–E); claudin-1 basolateral membrane location, corresponding with tubules showing discrete junctional ZO-1 staining (arrowheads in A and D); robust ZO-1 staining was seen in glomerular epithelial cells (A); scale bar 100 µm].