Table 3.

Haplotype analysis of IL12B.

Block 1a		Frequency Cases	Frequency Controls	p value
1	A-G-T-S-G-G	0.63	0.62	0.61
2	C-G-C-L-T-C	0.25	0.24	0.49
3	A-A-T-S-G-G	0.06	0.09	0.02
4	C-G-C-L-T-G	0.03	0.04	0.38
Global significanceb				0.11

^a The order of the SNPs in each block corresponds to Figure 1, with D5S2941 included and rs3213096 excluded due to its low allele frequency in the SAC population.

^b Global significance were calculated in COCAPHASE [38] and 10 000 permutations were done.