Table 4. Selected SNPs reaching genome-wide significance for replications of eye color associations.
| Phenotype | SNP | Chr | Position | Locus | Alleles | MAF | Score | BF |
|
OR |
| Eye color | rs12913832 | 15 | 26,039,213 | OCA2 | G/A | 0.23 |
|
|
2.491 | — |
| rs8039195 | 15 | 26,189,679 | OCA2 | T/C | 0.14 | 291.35 | 293.35 | 2.088 | — | |
| rs16950987 | 15 | 26,199,823 | OCA2 | G/A | 0.05 | 125.44 | 121.47 | 2.169 | — | |
| rs2240204 | 15 | 26,167,627 | OCA2 | G/A | 0.05 | 117.51 | 113.57 | 2.127 | — | |
| rs6497253 | 15 | 25,962,144 | OCA2 | G/A | 0.21 | 43.47 | 40.32 | 0.710 | — | |
| rs1470608 | 15 | 25,961,716 | OCA2 | G/T | 0.14 | 42.49 | 39.33 | 0.839 | — | |
| rs4778232 | 15 | 25,955,360 | OCA2 | C/T | 0.21 | 38.75 | 35.90 | 0.663 | — | |
| rs1597196 | 15 | 25,968,517 | OCA2 | G/T | 0.17 | 31.88 | 28.81 | 0.648 | — | |
| rs7170451 | 15 | 25,865,819 | OCA2 | G/A | 0.27 | 26.48 | 23.52 | 0.503 | — | |
| rs1800407 | 15 | 25,903,913 | OCA2 | C/T | 0.08 | 23.49 | 20.78 | 0.823 | — | |
| rs4778220 | 15 | 25,894,733 | OCA2 | A/G | 0.17 | 20.58 | 17.83 | 0.531 | — | |
| rs728405 | 15 | 25,873,448 | OCA2 | A/C | 0.22 | 19.91 | 17.34 | 0.466 | — | |
| rs1800404 | 15 | 25,909,368 | OCA2 | T/C | 0.21 | 14.47 | 11.91 | 0.411 | — | |
| rs1107267 | 15 | 25,645,234 | OCA2 | G/A | 0.26 | 11.76 | 10.33 | 0.338 | — | |
| rs3930739 | 15 | 25,713,937 | OCA2 | C/T | 0.46 | 11.38 | 8.96 | −0.288 | — | |
| rs17565953 | 15 | 25,692,250 | OCA2 | G/T | 0.40 | 10.94 | 8.68 | −0.289 | — | |
| rs977588 | 15 | 25,852,901 | OCA2 | A/C | 0.41 | 8.55 | 6.48 | 0.252 | — | |
| rs12896399 | 14 | 91,843,416 | SLC24A4 | G/T | 0.44 | 15.95 | 13.49 | −0.343 | — | |
| rs4904868 | 14 | 91,850,754 | SLC24A4 | C/T | 0.45 | 13.49 | 10.95 | 0.317 | — | |
| rs12203592 | 6 | 341,321 | IRF4 | C/T | 0.18 | 14.69 | 13.26 | −0.424 | — | |
| rs16891982 | 5 | 33,987,450 | SLC45A2 | G/C | 0.03 | 11.83 | 9.42 | 0.840 | — | |
| rs1393350 | 11 | 88,650,694 | TYR | G/A | 0.27 | 8.49 | 6.25 | −0.278 | — | |
| Green eyes | rs12913832 | 15 | 26,039,213 | OCA2 | G/A | 0.23 | 51.52 | 41.34 | 2.131 | 8.425 |
| rs7183877 | 15 | 26,039,328 | OCA2 | C/A | 0.08 | 29.54 | 21.57 | 2.275 | 9.732 | |
| rs12896399 | 14 | 91,843,416 | SLC24A4 | G/T | 0.44 | 22.82 | 19.49 | −0.546 | 0.579 | |
| rs1847134 | 11 | 88,644,901 | TYR | A/C | 0.32 | 14.95 | 13.13 | −0.461 | 0.631 | |
| rs1827430 | 11 | 88,658,088 | TYR | A/G | 0.38 | 10.97 | 8.93 | −0.377 | 0.686 | |
| rs11018528 | 11 | 88,570,025 | TYR | A/G | 0.30 | 10.48 | 8.73 | −0.391 | 0.676 | |
| rs7120151 | 11 | 88,380,027 | TYR | G/A | 0.29 | 9.61 | 8.19 | −0.375 | 0.687 | |
| rs1806319 | 11 | 88,677,584 | TYR | T/C | 0.37 | 9.35 | 7.37 | −0.348 | 0.706 |
See Table 2 for details. Eye color was coded on a seven point scale from blue to brown. Green eye color was treated as a binary trait, where cases had green eyes and controls blue.