Table 3.

Differentially up-regulated proteins listed in the UniProt database as involved in lipid synthesis or metabolism in ITRAQ analysis 1.

SwissProt acc. no.	Name	Subcellular location	Relative expression compared to Nrf2(+/+) mouse 1
Nrf2(+/+)		Nrf2(−/−)		Fold change Nrf2(−/−) Nrf2(+/+)	p
Geometric mean	95% CI	Geometric mean	95% CI
Q05816	Fatty acid-binding protein, epidermal	C	1.02	(0.87–1.18)	3.02	(2.61–3.50)	2.97	0.009
Q8VCH0	3-Ketoacyl-CoA thiolase B, peroxisomal	P	1.41	(1.09–1.82)	3.35	(2.88–3.91)	2.39	0.044
P13516	Acyl-CoA desaturase 1	ER	1.17	(1.00–1.36)	2.41	(1.62–3.59)	2.07	0.153
Q91V92	ATP-citrate synthase	C	1.07	(1.01–1.12)	1.90	(1.80–2.01)	1.78	0.003
Q8JZR0	Long-chain-fatty-acid-CoA ligase 5	ER, Mi	0.96	(0.91–1.02)	1.47	(1.29–1.69)	1.53	0.044
Q9DBM2	Peroxisomal bifunctional enzyme	P	1.16	(1.02–1.31)	1.65	(1.54–1.76)	1.43	0.057
Q99P30	Peroxisomal coenzyme A diphosphatase NUDT7	P	1.04	(0.93–1.16)	1.48	(1.40–1.57)	1.43	0.044
Q9QXD1	Peroxisomal acyl-coenzyme A oxidase 2	P	1.23	(1.07–1.42)	1.74	(1.57–1.93)	1.41	0.117
Q9R0H0	Peroxisomal acyl-coenzyme A oxidase 1	P	1.00	(0.95–1.05)	1.31	(1.29–1.33)	1.31	0.009
P19096	Fatty acid synthase	C	1.07	(1.00–1.13)	1.39	(1.35–1.43)	1.30	0.022
P32020	Non-specific lipid-transfer protein	C	1.15	(1.02–1.31)	1.48	(1.42–1.55)	1.29	0.117
Q61425	Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial	Mi	1.01	(0.99–1.04)	1.28	(1.12–1.46)	1.26	0.156
P31786	Acyl-CoA-binding protein	Mi	0.90	(0.83–0.97)	1.14	(1.06–1.22)	1.26	0.073
P50172	Corticosteroid 11-beta-dehydrogenase isozyme 1	ER	1.06	(0.98–1.16)	1.31	(1.23–1.39)	1.23	0.103
Q9QXE0	2-Hydroxyacyl-CoA lyase 1	P	0.93	(0.84–1.02)	1.12	(1.08–1.16)	1.20	0.117