Table 5.
Metacore network analysis of data from iTRAQ analysis 1.
| Pathway name | Negative log p value | Number of pathway objects | |
|---|---|---|---|
| 1 | n-6 Polyunsaturated fatty acid biosynthesis | 2.52 | 5 |
| 2 | n-3 Polyunsaturated fatty acid biosynthesis | 2.52 | 5 |
| 3 | Regulation of lipid metabolism_Regulation of lipid metabolism via LXR, NF-Y and SREBP | 2.44 | 3 |
| 4 | Vitamin E (alfa-tocopherol) metabolism | 1.98 | 5 |
| 5 | Regulation of metabolism_Bile acids regulation of glucose and lipid metabolism via FXR | 1.89 | 4 |
| 6 | Fatty Acid Omega Oxidation | 1.64 | 4 |
| 7 | Peroxysomal straight-chain fatty acid beta-oxidation | 1.64 | 4 |
| 8 | CFTR-dependent regulation of ion channels in Airway Epithelium (norm and CF) | 1.62 | 2 |
| 9 | Cell cycle_Role of SCF complex in cell cycle regulation | 1.62 | 2 |
| 10 | Glutathione metabolism/Rodent version | 1.3 | 5 |
Proteins identified in iTRAQ analysis 1 as being differentially expressed (Benjamini-Hochberg p ≤ 0.2) were interrogated for pathway perturbation using the pathway analysis software Metacore. The total list of all quantified proteins was applied as a background for the analysis.