TABLE 4.

Baseline clinical characteristics of male patients with type 1 diabetes and microalbuminuria with and without progression to macroalbuminuria

	Non-progressors	Progressors	P-value
N	59	37
Age (yrs)	37.0 ± 9.5	36.0 ± 10.4	0.629
Duration of diabetes (yrs)	24.5 ± 8.4	26.4 ± 10.5	0.350
BMI (kg/m2)	25.3 ± 3.3	25.5 ± 3.6	0.763
WHR	0.91 ± 0.06	0.93 ± 0.06	0.070
Systolic BP (mmHg)	133 ± 15	139 ± 14	0.063
Diastolic BP (mmHg)	81 ± 10	84 ± 10	0.135
AHT (%)	71.2	67.6	0.707
HbA1c (%)	8.6 ± 1.4	9.7 ± 2.0	0.003
Triglycerides (mmol/l)	1.05 (0.57 – 4.10)	1.72 (0.60 – 8.82)	<0.001
Total cholesterol (mmol/l)	4.73 ± 0.79	5.34 ± 0.96	0.001
HDL-cholesterol (mmol/l)	1.27 ± 0.34	1.14 ± 0.32	0.083
eGFR (ml/min/1.73m2)	96.7 ± 18.4	100.0 ± 28.8	0.496
uAER (mg/24h)	46 (6 – 184)	152 (59 – 483)	<0.001
eGDR (mg/kg/min)	4.41 ± 1.51	3.55 ± 1.69	0.012
Tt (ng/ml)	5.30 (0.91 – 11.42)	4.26 (1.45 – 9.23)	0.043
cFt (ng/ml)	0.047 (0.020 – 0.229)	0.049 (0.016 – 0.175)	0.625
Te (pg/ml)	52.1 (11.3 – 2096)	48.3 (21.2 – 943)	0.530
cFe (pg/ml)	0.344 (0.115 – 19.650)	0.504 (0.193 – 10.010)	0.062
SHBG (nmol/l)	112.9 ± 52.2	84.6 ± 43.0	0.007

Data are presented as means ± SD, medians with range or percentages when appropriate.