TABLE 6.

Cox regression models for progression in renal status: A) from normal AER to microalbuminuria, B) from microalbuminuria to macroalbuminuria, and C) from macroalbuminuria to end-stage renal disease (ESRD).

Model A
Variable	Hazard ratio (95%CI)	P-value
Duration of diabetes (yrs)	0.97 (0.93 – 1.02)	0.213
WHR	557.96 (1.65 – 188561.26)	0.033
HbA_1c (%)	1.37 (1.09 – 1.72)	0.008
ln(Triglycerides)	0.95 (0.61 – 1.71)	0.982
eGDR (mg/kg/min)	1.15 (0.92 – 1.44)	0.214
ln(cFt)	0.89 (0.41 – 1.96)	0.776
ln(cFe)	1.01 (0.68 – 1.49)	0.945
SHBG (nmol/l)	1.00 (0.99 – 1.01)	0.666

Model B
Variable	Hazard ratio (95%CI)	P-value
Systolic blood pressure (mmHg)	1.02 (1.00 – 1.05)	0.096
WHR	0.04 (0.01 – 726.67)	0.529
HbA_1c (%)	1.17 (0.91 – 1.51)	0.230
ln(Triglycerides)	3.44 (1.48 – 8.04)	0.004
eGDR (mg/kg/min)	0.93 (0.65 – 1.33)	0.690
ln(cFt)	0.43 (0.19 – 0.95)	0.036
ln(cFe)	1.18 (0.77 – 1.81)	0.445
SHBG (nmol/l)	1.00 (0.99 – 1.01)	0.822

Model C
Variable	Hazard ratio (95%CI)	P-value
ln(cFe)	3.03 (1.67 – 5.50)	<0.001
eGFR (ml/min/1.73m²)	0.95 (0.93 – 0.97)	<0.001
ln(cFt)	0.46 (0.22 – 0.96)	0.038
ln(Triglycerides)	1.68 (0.93 – 3.02)	0.085
SHBG (nmol/l)	1.01 (1.00 – 1.01)	0.221