Table 1.

Induction of VDR-target genes by 1,25D and CM in Caco-2 cells as measured via real-time PCR.

Gene	Ligand	Average (± S.D.) Relative Fold Increase in Target Gene mRNA (n=3)
		Endogenous VDR	Co-transfected VDR
CYP3A4 (Xenobiotic detoxification)	+D (10−7 M)	1.55 ± 0.29	3.10 ± 0.56
	+CM (5 × 10−5 M)	1.41 ± 0.19	3.02 ± 0.64
p21 (Cell differentiation and division)	+D (10−7 M)	1.22 ± 0.09	2.52 ± 0.45
	+CM (5 × 10−5 M)	7.91 ± 1.67	11.58 ± 1.92
TRPV6 (Intestinal calcium transport)	+D (10−7 M)	2.41 ± 0.53	5.32 ± 1.12
	+CM (5 × 10−5 M)	2.17 ± 0.44	4.11 ± 0.98