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. Author manuscript; available in PMC: 2011 May 1.
Published in final edited form as: J Thromb Haemost. 2010 Feb 17;8(5):1107–1115. doi: 10.1111/j.1538-7836.2010.03812.x

Figure 4.

Figure 4

Effects of different proteases on the expression of Tie2, Ang1, and Ang2 proteins. Primary HUVECs were incubated with indicated proteases (2 nM thrombin, 20 nM APC or GD-APC) for 16h with (black bars) or without (white bars) sequential treatment with MβCD (10 mM, 1h) and PC-S195A (50 nM, 30 min) followed by measuring expression levels of Tie2 (A) Ang1 (B) and Ang2 (C) by ELISA. *p< 0.05 as compared to without MβCD.