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Final model examining WML volume change and AGTR1 genotype
| Variable | F value | p value |
|---|---|---|
| AGTR1 | 10.19 | 0.0016 |
| Depression Diagnosis | 0.29 | 0.5906 |
| Age | 4.14 | 0.0429 |
| Baseline Lesion Volume | 74.86 | < 0.0001 |
| Hypertension | 0.20 | 0.6531 |
| Sex | 0.01 | 0.9101 |
| AGTR1 – Sex Interaction | 3.93 | 0.0488 |
Model variables determined through backwards regression. AGTR1 genotype, depression diagnosis, and hypertension were designated as variables that had to remain in the model.
