Table 3.
Unadjusted and demographic adjusted associations with atrial fibrillation in logistic regression analysis
| Model 1: Unadjusted | Model 2: demographic adjusted | |||
|---|---|---|---|---|
| Odds Ratio (95% CI)* | P-value | Odds Ratio (95% CI)** | P-value | |
| Age (years)*** | 1.03 (1.02– 1.04) | <.0001 | 1.46 (1.32– 1.62) | <.0001 |
| Female sex | 0.98 (0.82– 1.16) | 0.7805 | 0.90 (0.75– 1.09) | 0.2875 |
| Race (Non-Hispanic black vs. Non-Hispanic white) | 1.24 (1.04– 1.49) | 0.0157 | 1.25 (1.03– 1.52) | 0.0228 |
| Education (Reference: post high school education) | 0.0452 | |||
| Less than high school graduate | 1.40 (1.09– 1.80) | 0.0086 | 1.13 (0.86– 1.47) | |
| High school graduate | 0.86 (0.67– 1.12) | 0.2673 | 0.78 (0.60– 1.01) | |
| College graduate | 0.80 (0.61– 1.04) | 0.0990 | 0.85 (0.65– 1.13) | |
| Post graduate degree | 0.69 (0.51– 0.93) | 0.0162 | 0.73 (0.53– 1.00) | |
| Total cholesterol (mg/dl)*** | 1.00 (0.99– 1.00) | 0.0006 | 0.85 (0.77– 0.94) | 0.0014 |
| Uric acid (mg/dl)*** | 1.04 (1.00– 1.09) | 0.0716 | 1.01 (0.92– 1.11) | 0.8366 |
| Estimated glomerular filtration rate (eGFR) ml/min/1.73 m2 (eGFR<45 vs >= 45) | 1.35 (1.13– 1.62) | 0.0010 | 1.12 (0.92– 1.35) | 0.2710 |
| High sensitivity C-reactive protein (mg/dL)*** | 1.00 (1.00– 1.01) | 0.2751 | 1.02 (0.94– 1.12) | 0.5922 |
| Body mass index (kg/m^2)*** | 1.01 (1.00– 1.02) | 0.0398 | 1.09 (1.00– 1.20) | 0.0599 |
| Physical activity: Total MET/hours/week*** | 1.00 (1.00– 1.00) | <.0001 | 0.85 (0.76– 0.95) | 0.0056 |
| Smoking status (Reference Never) | 0.0001 | |||
| Current | 1.38 (1.04– 1.82) | 0.0237 | 1.30 (0.98– 1.73) | |
| Former | 1.78 (1.46– 2.16) | <.0001 | 1.56 (1.27– 1.91) | |
| Alcohol use (drinker vs. nondrinkers) | 0.75 (0.62– 0.90) | 0.0022 | 0.87 (0.71– 1.06) | 0.1678 |
| Hypertension | 1.18 (0.91– 1.54) | 0.2201 | 0.83 (0.63– 1.11) | 0.2036 |
| Diabetes | 1.25 (1.05– 1.49) | 0.0139 | 1.11 (0.92– 1.33) | 0.2828 |
| Congestive heart failure | 5.63 (4.43– 7.14) | <.0001 | 5.20 (4.06– 6.67) | <.0001 |
| Any cardiovascular disease | 3.48 (2.90– 4.17) | <.0001 | 3.06 (2.53– 3.71) | <.0001 |
*
Odds ratios represent unadjusted association of individual variables in the first column with AF
**
Odds ratios represent age, sex, race/ethnicity and clinical center adjusted associations of the individual variables in the first column with AF each variable
***
Odds ratios for continuous variables are for 1-SD increase