Table 1.
Regulated phosphoproteins with TiO2 enrichment
| IPI no. | Gene name | Description | Location | M-44 | NM-2C5 | Ratio of mean (M-4A4/NM-2C5) | p value | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Spectral counts | |||||||||||||||||
| R1a | R2 | R3 | R4 | R5 | R6 | R1 | R2 | R3 | R4 | R5 | R6 | ||||||
| IPI00021812 | AHNAK | Neuroblast differentiation-associated protein AHNAK (Fragment) | Nucleus | 2 | 1 | 1 | 2 | 6 | 4 | 7 | 8 | 7 | 10 | 0.18 | 2.44E-03 | ||
| IPI00186966 | BIN1 | Isoform IIA of Myc box-dependent-interacting protein 1 | Nucleus | 2 | 2 | 2 | 2 | 2 | 2 | 1 | 1 | 2 | 2 | 2.45 | 1.74E-02 | ||
| IPI00013743 | BUD13 | BUD13 homolog | Nucleus | 8 | 5 | 6 | 6 | 7 | 4 | 7 | 7 | 5 | 5 | 5 | 4 | 1.33 | 3.54E-02 |
| IPI00296432 | IWS1 | Isoform 1 of IWS1 homolog | Nucleus | 5 | 6 | 5 | 6 | 8 | 7 | 9 | 6 | 6 | 4 | 6 | 4 | 1.33 | 3.68E-02 |
| IPI00017297 | MATR3 | Matrin-3 | Nucleus | 5 | 4 | 5 | 3 | 4 | 5 | 6 | 3 | 4 | 2 | 3 | 4 | 1.48 | 1.80E-02 |
| IPI00306933 | MYO9B | Isoform Short of Myosin-IXb | Cytoplasm | 4 | 4 | 3 | 4 | 4 | 2 | 2 | 2 | 3 | 1 | 3.05 | 1.65E-02 | ||
| IPI00022078 | NDRG1 | Protein NDRG1 | Nucleus | 8 | 8 | 12 | 10 | 11 | 10 | 7 | 6 | 7 | 6 | 7 | 5 | 1.89 | 1.92E-04 |
| IPI00012345 | SFRS6 | Isoform SRP55-1 of Splicing factor, arginine/serine-rich 6 | Nucleus | 6 | 8 | 8 | 10 | 9 | 8 | 5 | 8 | 7 | 5 | 7 | 7 | 1.55 | 5.58E-03 |
| IPI00100151 | XRN2 | Isoform 1 of 5′-3′exoribonuclease 2 | Nucleus | 6 | 7 | 8 | 8 | 8 | 10 | 7 | 8 | 4 | 5 | 7 | 5 | 1.65 | 1.27E-03 |
| IPI00219866 | ZRANB2 | Isoform ZIS-2 of Zinc finger Ran-binding domain-containing protein 2 | Nucleus | 5 | 4 | 5 | 4 | 5 | 5 | 4 | 4 | 4 | 3 | 4 | 5 | 1.43 | 1.34E-03 |
| Regulated phosphoproteins with ZrO2 enrichment | |||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IPI no. | Gene name | Description | Location | M-4A4 | NM-2C5 | Ratio of mean (M-4A4/NM-2C5) | p value | ||||||||||
| Spectral counts | |||||||||||||||||
| R1 | R2 | R3 | R4 | R5 | R6 | R1 | R2 | R3 | R4 | R5 | R6 | ||||||
| IPI00550363 | TAGLN2 | Transgelin-2 | Cytoplasm | 1 | 1 | 1 | 2 | 2 | 2 | 2 | 2 | 3 | 0.22 | 9.00E-04 | |||
| IPI00021812 | AHNAK | NEUROBLAST DIFFERENTIATION-ASSOCIATED PROTEIN AHNAK | Nucleus | 4 | 5 | 6 | 4 | 1 | 5 | 12 | 14 | 17 | 8 | 15 | 13 | 0.26 | 7.45E-05 |
| IPI00220113 | MAP4 | microtubule-associated protein 4 | Cytoplasm | 2 | 1 | 3 | 1 | 1 | 3 | 3 | 3 | 2 | 4 | 4 | 0.37 | 1.36E-02 | |
| IPI00020956 | HDGF | hepatoma-derived growth factor (high-mobility group protein 1-like) | Extracellular | 1 | 3 | 3 | 1 | 1 | 2 | 3 | 5 | 2 | 4 | 4 | 0.38 | 1.02E-02 | |
| IPI00299254 | EIF5B | eukaryotic translation initiation factor 5B | Cytoplasm | 3 | 3 | 3 | 2 | 3 | 7 | 5 | 6 | 3 | 3 | 4 | 0.39 | 3.22E-02 | |
| IPI00304742 | STK10 | SERINE/THREONINE-PROTEIN KINASE 10 | Cytoplasm | 1 | 1 | 3 | 2 | 4 | 3 | 2 | 2 | 2 | 1 | 0.40 | 4.06E-02 | ||
| IPI00015029 | PTGES3 | Prostaglandin E synthase 3 | Cytoplasm | 7 | 5 | 5 | 7 | 8 | 7 | 8 | 10 | 6 | 8 | 13 | 8 | 0.65 | 2.98E-02 |
| IPI00010276 | OGFOD2 | SRp25 nuclear protein isoform 2 | Unknown | 2 | 3 | 2 | 2 | 1 | 1 | 2 | 2 | 4 | 2 | 2 | 2 | 0.66 | 3.54E-02 |
| IPI00297178 | DHX16 | DEAH (Asp-Glu-Ala-His) box polypeptide 16 | Nucleus | 2 | 2 | 1 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 3 | 3 | 0.69 | 2.93E-02 |
| IPI00102875 | ZFYVE19 | Isoform 3 of Zinc finger FYVE domain-containing protein 19 | Unknown | 2 | 2 | 2 | 1 | 1 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 0.69 | 1.08E-02 |
| IPI00006038 | NUP98 | Isoform 1 of Nuclear pore complex protein Nup98-Nup96 precursor | Nucleus | 3 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 3 | 3 | 4 | 2 | 0.71 | 2.49E-02 |
| IPI00021405 | LMNA | lamin A/C | Nucleus | 14 | 19 | 15 | 22 | 10 | 21 | 9 | 8 | 11 | 12 | 7 | 9 | 1.50 | 7.59E-03 |
| IPI00012442 | G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | Nucleus | 5 | 4 | 3 | 4 | 4 | 6 | 2 | 3 | 3 | 3 | 2 | 1 | 1.58 | 4.48E-02 |
| IPI00022078 | NDRG1 | Protein NDRG1 | Nucleus | 7 | 5 | 9 | 7 | 5 | 8 | 1 | 4 | 3 | 5 | 4 | 5 | 1.61 | 3.88E-02 |
| IPI00306933 | MYO9B | Isoform Short of Myosin-IXb | Cytoplasm | 4 | 3 | 3 | 6 | 2 | 7 | 1 | 2 | 2 | 3 | 3 | 2 | 1.62 | 4.43E-02 |
| IPI00020984 | CANX | calnexin | Cytoplasm | 5 | 5 | 4 | 5 | 3 | 3 | 1 | 2 | 3 | 2 | 4 | 1 | 1.68 | 1.99E-02 |
| IPI00104050 | THRAP3 | Thyroid hormone receptor-associated protein 3 | Nucleus | 2 | 2 | 2 | 2 | 1 | 2 | 2 | 1 | 1 | 1.95 | 2.99E-02 | |||
| IPI00221394 | DKC1 | dyskeratosis congenita 1, dyskerin | Nucleus | 4 | 2 | 3 | 2 | 2 | 4 | 2 | 1 | 2 | 2 | 2.11 | 4.46E-02 | ||
| IPI00019996 | SLTM | modulator of estrogen induced transcription isoform b | Nucleus | 2 | 3 | 2 | 2 | 2 | 2 | 1 | 1 | 1 | 3.33 | 3.29E-03 | |||
| IPI00297579 | CBX3 | CHROMOBOX PROTEIN HOMOLOG 3 | Nucleus | 2 | 2 | 7 | 5 | 3 | 8 | 3 | 1 | 1 | 3.81 | 8.64E-03 | |||
a
MS2 run