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. Author manuscript; available in PMC: 2010 Jun 25.
Published in final edited form as: Gastroenterology. 2008 Jul 17;135(3):756–769. doi: 10.1053/j.gastro.2008.05.048

Figure 2.

Figure 2

Methodology for quantifying deglutitive EGJ relaxation within the relaxation window detailed in Figure 1. (A) Cumulative duration of EGJ relaxation in seconds as the relaxation pressure cutoff was increased; for example, for a relaxation pressure cutoff of 10 mmHg, the EGJ residual pressure was equal to or less than this value for about 5 seconds. (B) An x–y transposition of A illustrating the marginal relaxation pressure as the specified duration of relaxation is increased from 0 to 10 seconds. This plot was used to calculate the 4-second IRP value (indicated) which is the integral of the curve (shaded) divided by 4 seconds. The 3-second nadir eSleeve measure of deglutitive relaxation is quantitatively similar to the 4-second IRP value, but has the requirement that the relaxation period analyzed be contiguous leaving it subject to crural diaphragm artifact in individuals with rapid respiration.