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. Author manuscript; available in PMC: 2010 Dec 1.
Published in final edited form as: Oncogene. 2010 May 3;29(25):3703–3714. doi: 10.1038/onc.2010.118

Figure 1.

Figure 1

Overexpression of Keap1 in HepG2 cells drives down Nrf2 levels and is accompanied by increased colony forming ability, as well as morphological plasticity. A) Immunoblot of cells stably expressing FLAG/Luciferase or FLAG/Keap1; B) Colony forming ability; C) Cell proliferation. Cells expressing FLAG/Luciferase exhibited a doubling time of approximately 31 hrs. Cells expressing FLAG/Keap1 exhibited a doubling time of approximately 24 hrs; D) Light microscopic images (200 × magnification).