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. Author manuscript; available in PMC: 2010 Jun 25.
Published in final edited form as: Phys Biol. 2010 May 26;7(2):026008. doi: 10.1088/1478-3975/7/2/026008

Figure 1.

Figure 1

(A) The geometry considered in this paper. A cluster of VDCCs emits calcium molecules into the pre-synaptic space where they can bind to mobile buffers. A calcium sensor, indicated in green, controls the release of vesicles and is located at a variable distance from the VDCC cluster. (B) The computational geometry, representing the synaptic space in the simulations, has a dimension of 4 μm × 0.5 μm × 0.5 μm. The faces of the space are covered uniformly by PCMA pumps. (C) Average time-dependent calcium concentration of a single voltage-gated channel. The concentration was measured in a 25 nm3 voxel adjacent to the channel.