Table 1.
Demographic and clinical characteristics of the Graves Ophthalmopathy subgroups and Control group
| Parameters | Control group (C) (n= 25) | Study group (S) (n=35) | Statistical analysis* | |
|---|---|---|---|---|
| Proptosis (P) (n=20) | Muscle restriction (M) (n=15) | |||
| Mean Age± SD (years) | 51.31± 3.51 | 53.42± 4.51 | 55.37± 1.42 | F=5.46 |
| P=0.54 | ||||
| Residence: | ||||
| Rural | 18(72) | 11(55) | 9(60) | χ2=0.004 |
| Urban | 7(28) | 9(45) | 6(40) | P=0.23 |
| Gender: | ||||
| Female | 17(68) | 12(60) | 9(60) | χ2=0.005 |
| Male | 8(32) | 8(40) | 6(40) | P=0.34 |
| Marital states: | ||||
| Married | 13(52) | 9(45) | 9(60) | F=6.45 |
| Single | 8(32) | 7(35) | 4(27) | P=0.56 |
| Widowed divorced | 4(16) | 4(20) | 2(13) | |
| Duration of GO (months) | ||||
| 0-6 | 14(56) | 12(60) | 8(53) | χ2=0.006 |
| 6-18 | 11(44) | 8(40) | 7(47) | P=0.38 |
| General: | ||||
| Fatigue | 14(56) | 8(40) | 6(40) | F=5.67 |
| Inappropriate weight gain | 8(32) | 4(20) | 4(26) | P=0.31 |
| Palpitation** | 11(44) | 7(35) | 6(40) | |
| Smoking | 8(32) | 4(20) | 0 | |
| Ocular | ||||
| Eyelid retraction | 13(52) | 4(40) | 8(53) | F=4.76 |
| Visual field defect | 11(44) | 5(25) | 4(26) | P=0.47 |
| Diplopia | 8(32) | 3(15) | 4(26) | |
| Optic atrophy | 0 | 2(10) | 2(13) | |
| Prior systemic steroid therapy | 14(56) | 7(35) | 6(40) | |
| Prior systemic radiotherapy | 3(12) | 4(20) | 3(20) | |
| Prior steroid and radiotherapy | 2(8) | 3(15) | 3(20) | |
| Prior orbital / lid / muscle surgery | 0 | 1(5) | 1(6) | |
| Psychiatric: | ||||
| Family history of psychiatric disorder | 3(12) | 2(10) | 0 | F=2.57 |
| Past history of psychiatric disorder | 2(8) | 0 | 2(13) | P=0.41 |
| Past history of medication intake | 6(24) | 5(25) | 3(20) | |
F=One Way Analysis of variance test, χ2 denotes Chi-square test, P≤0.05 was considered statistically significant
**
Palpitation = greater than or equal to 110 per minute