Table 2.
Relative levels of pro-angiogenesis cytokines/receptors induced by leptin in endometrial epithelial cells (EEC)
Cell type |
VEGF |
VEGFR2 |
LIF |
LIFR |
IL-1 |
IL-1R tl |
---|---|---|---|---|---|---|
Primary EEC | n.s. | n.s. | 1.5a | 3.0a | 8.5a | 1.9a |
HES | n.s. | 1.6a | n.s. | 2.0a | n.s. | 1.4a |
Ishikawa | 1.7a | 1.8a | 2.2a | 1.5a | n.s. | 2.0a |
SK-UT2 | 1.5a | 6.2a | n.s. | n.s. | n.s. | 5.0a |
An3Ca | 1.4a | 1.5a | 4.9a | 7.0a | n.s. | 20a |
Note: The data represent fold differences for quantitative analysis of cytokines determined by ELISA and densitometric calculations from Western blot of cytokine receptors expressed by EEC after incubation for 24 h with leptin (62.5 nM). The Western blot data were normalized to β-actin on a fold difference from control (basal medium; n ≥ 3). (n.s.) no significant difference with respect to control
P <0.05 significant difference with respect to control.