Fig. 1.

Known regulatory regions within and flanking the IL10 gene. In the top panel, the physical organization of the IL10 cluster is displayed, including intergenic regions and distances between all genes in the cluster. The lower panel displays regions of epigenetic remodelling that have been investigated by various groups and in different cellular subsets. The tables beneath the figure explain the used symbols and give an overview on the cellular subsets and specific epigenetic modifications in each investigated region