Table 1.

Therapeutic transdermal fluxes and transition times for nicotine and clonidine (n = 4).

	Concentration (mg/ml)	Transdermal flux (μmol/cm2/h)	Transition time (min)
Nicotine	500	4.27 ± 0.22	4.7 ± 0.4
	50	1.48 ± 0.22	0
	500	4.23 ± 0.25	5.5 ± 0.5
Clonidine	0.225	0.0037 ± 0.00100	322 ± 59*
	0.325	0.0053 ± 0.00068	N/A
	0.160	0.0021 ± 0.00096	N/A

^*Initial lag time for the first dose.