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. Author manuscript; available in PMC: 2011 May 25.
Published in final edited form as: Biochemistry. 2010 May 25;49(20):4374–4382. doi: 10.1021/bi100252s

Table 2.

Kinetic Parameters for Isoxanthopterin and Pterin-6-carboxylate Deamination with Sgx9339a and Sgx9236b.

enzyme substrate kcat (s−1) Km (mM) kcat/Km (M−1 s−1)
Sgx9339a isoxanthopterin 1.05 ± 0.03 0.008 ± 0.001 (1.3 ± 0.2) × 105
pterin-6-carboxylate 1.01 ± 0.10 0.14 ± 0.02 (7.2 ± 0.2) × 103
Sgx9236b isoxanthopterin 0.91 ± 0.06 0.05 ± 0.01 (1.8 ± 0.2) × 104
pterin-6-carboxylate 0.28 ± 0.05 0.09 ± 0.03 (3.1 ± 0.4) × 103