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Inhibition by Ab-01 at the indicated concentration is shown for 6 IL21-responsive genes. IC50 values of inhibition curves shown in Figure 4A were calculated using curve fit (XLfit) program for each of the referred biomarker genes. Values for the 0.1 μg/mL, 0.3 μg/mL and 1 μg/mL concentrations were generated using 4 donors. Data for the higher and the lower concentrations were generated using 2 donors each.
