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. 2010 Jun 11;7:34. doi: 10.1186/1742-2094-7-34

Figure 1.

Figure 1

CSF CHI3L1 levels in neurodegenerative diseases and stroke. CSF samples from MS, AD, ALS, stroke and control patients were analyzed for CHI3L1 using the CHI3L1 ELISA kit. The Mann-Whitney test was used to evaluate group differences (*P < 0.05, **P < 0.001, ***P < 0.0001). CSF YKL-40 levels in MS patients were significantly elevated compared to young, age-matched controls (A). While all neurodegenerative diseases and stroke show difference from young controls, AD, ALS and stroke patients do not show significant differences when compared to older age-matched controls (B).