Table 1.
CSF CHI3L1 levels in neurodegenerative diseases.
| Condition (n) | Age range (median) | CHI3L1 concentration (range, ng/ml) | CHI3L1 concentration (median, ng/ml) |
|---|---|---|---|
| Healthy young controls (n = 12) | <40 | 67-256 | 109 |
| MS (n = 10) | 28-58 (48) | 152-697 | 281 |
| Aged healthy controls (n = 7) | 60-70 (65) | 139-257 | 218 |
| AD (n = 10) | 59-86 (75) | 153-1230 | 212 |
| ALS (n = 10) | 32-74 (62.5) | 75-769 | 388 |
| Stroke (n = 10) | 60-89 (72) | 160-1065 | 359 |
CSF samples from MS, AD, ALS, stroke and control patients were analyzed for CHI3L1 using the MicroVue CHI3L1 ELISA kit.