Table 2.
MicroRNAs differentially expressed between refractory (NR) and sensitive (CR) patients before Fludarabine treatment
| PRE Treatment Differentially expressed microRNAs | |||||||
|---|---|---|---|---|---|---|---|
| microRNA | p-value | Fold change absolute | Regulation NR/CR | NR average expression | CR average expression | Chromosome | Accession |
| hsa-miR-31 | 0.0091 | 2.21 | down | 1.14 | 2.51 | chr9 | MIMAT0000089 |
| hsa-miR-125b | 0.0233 | 1.72 | down | 1.17 | 2.02 | chr11 | MIMAT0000423 |
| hsa-miR-10a | 0.0234 | 1.85 | down | 1.08 | 1.99 | chr17 | MIMAT0000253 |
| hsa-miR-181d | 0.0452 | 1.29 | down | 1.49 | 1.92 | chr19 | MIMAT0002821 |
| hsa-miR-126* | 0.0462 | 1.18 | down | 1.14 | 1.35 | chr9 | MIMAT0000444 |
| hsa-miR-21* | 0.0068 | 3.65 | up | 8.13 | 2.23 | chr17 | MIMAT0004494 |
| hsa-miR-222 | 0.0096 | 2.12 | up | 70.59 | 33.31 | chrX | MIMAT0000279 |
| hsa-miR-28-3p | 0.0201 | 3.38 | up | 5.04 | 1.49 | chr3 | MIMAT0004502 |
| hsa-miR-194 | 0.0347 | 2.40 | up | 14.59 | 6.08 | chr1 | MIMAT0000460 |
| hsa-miR-148a | 0.0414 | 3.44 | up | 73.41 | 21.33 | chr7 | MIMAT0000243 |