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Expression of the ubiquitin genes in R6/2‐Ubc mice. Expression of the four ubiquitin genes was normal in 14 week (end‐stage) R6/2 striatum and cerebellum. Knockout of one Ubc allele can be seen to reduce the levels of Ubc expression in R6/2 and non‐R6/2 striatum and cerebellum. Although significant in cerebellum (P= 0.002) and cortex (data not shown), this reduction of Ubc is not significant in the striatum (P= 0.147). Error bars show standard error of the mean.
