Skip to main content
. 2008 Oct 13;13(8b):2645–2657. doi: 10.1111/j.1582-4934.2008.00543.x

Figure 2.

Figure 2

Behavioural characterization of R6/2‐Ubc mice. (A) Rotarod performance of R6/2 mice is significantly worse than that of non‐R6/2 mice from 8 weeks of age onwards. Knocking out one copy of Ubc has no effect on the rotarod performance of R6/2 mice. (B) Grip strength of R6/2 mice is worse than non‐R6/2 mice from 5 weeks onwards. Knocking out one Ubc allele has no significant effect on R6/2 grip strength. (C) R6/2 mice weigh significantly less than non‐R6/2 mice, and genetic reduction of Ubc has no statistically significant effect on this. Error bars represent the standard error of the mean.