Figure 1. Representation of induced mutations in Sl-eIF4E1, Sl-eIF4E2, Sl-eIF(iso)4E, Sl-eIF4G and Sl-eIF(iso)4G.

Black boxes represent the exons. Lanes linking exons indicate introns. Dashed lines indicate the genomic regions screened for mutations. Triangles pointing up indicate mutations in coding regions, whereas those pointing down indicate mutations in noncoding regions. Red, black and grey triangles represent alterations causing truncations, missense and silent mutations, respectively. Only exons 7 to 9 are shown for Sl-eIF4G.