Table 2.
Selected Characteristics of Cases and Controls in the Investigation of Upper Gastrointestinal Cancer Within the Cohort Consortium Vitamin D Pooling Project of Rarer Cancers
Cases (N = 1,065) |
Controls (N = 1,066) |
||||||
Characteristic | No. | % | Median (Interquartile Range) | No. | % | Median (Interquartile Range) | P Valuea |
Age at blood draw, years | 61 (55–67) | 61 (55–66) | Matched | ||||
Sex | |||||||
Female | 290 | 27 | 290 | 27 | Matched | ||
Male | 775 | 73 | 776 | 73 | |||
Race/ethnic group | |||||||
Caucasian | 647 | 61 | 649 | 61 | Matched | ||
Black | 30 | 3 | 30 | 3 | |||
Asian | 350 | 33 | 349 | 33 | |||
Other | 35 | 3 | 36 | 3 | |||
Missing | 3 | <1 | 2 | <1 | |||
Cigarette smoking | |||||||
Never | 305 | 29 | 344 | 32 | 0.0001 | ||
Quit >15 years ago | 85 | 8 | 107 | 10 | |||
Quit 10–15 years ago | 62 | 6 | 40 | 4 | |||
Quit 1–<10 years ago | 39 | 4 | 28 | 3 | |||
Current, <20 cigarettes/day | 214 | 20 | 250 | 23 | |||
Current, ≥20 cigarettes/day | 352 | 33 | 291 | 27 | |||
Missing | 8 | <1 | 6 | <1 | |||
Alcohol intake, g/day | |||||||
None | 406 | 38 | 426 | 40 | 0.13 | ||
>0–14 | 284 | 27 | 316 | 30 | |||
>14–28 | 120 | 11 | 120 | 11 | |||
>28 | 153 | 14 | 122 | 11 | |||
Missing | 102 | 10 | 82 | 8 | |||
Education | |||||||
Less than high school | 440 | 41 | 384 | 36 | 0.0062 | ||
Completed high school | 157 | 15 | 164 | 15 | |||
Vocational school | 211 | 10 | 202 | 19 | |||
Some college | 160 | 15 | 186 | 18 | |||
College graduate | 47 | 4 | 71 | 7 | |||
Graduate studies | 40 | 4 | 51 | 5 | |||
Missing | 10 | 1 | 8 | 1 | |||
Body mass index, kg/m2 | 25.3 (22.9–28.2) | 25.3 (23.1–28.1) | 0.51 | ||||
History of gastric surgery | |||||||
No | 620 | 58 | 758 | 71 | 0.0003 | ||
Yes | 41 | 4 | 16 | 2 | |||
Missing | 404 | 38 | 292 | 27 | |||
Season of blood draw | |||||||
Winter | 560 | 53 | 556 | 52 | 0.55 | ||
Summer | 505 | 47 | 510 | 48 | |||
Serum 25(OH)D concentration, nmol/L | 39.4 (26.3–56.1) | 39.1 (25.8–56.7) | 0.90 | ||||
Serum 25(OH)D concentration category, nmol/L | |||||||
<25 | 241 | 22.7 | 252 | 23.6 | 0.97 | ||
25–<37.5 | 248 | 23.2 | 239 | 22.4 | |||
37.5–<50 | 224 | 21.0 | 223 | 20.9 | |||
50–<75 | 249 | 23.4 | 252 | 23.6 | |||
75–<100 | 83 | 7.8 | 77 | 7.2 | |||
≥100 | 20 | 1.9 | 23 | 2.2 |
Abbreviation: 25(OH)D, 25-hydroxyvitamin D.
Wald test from conditional logistic regression, excluding subjects with missing data.