. 2010 Jun 18;172(1):94–106. doi: 10.1093/aje/kwq121

Table 3.

Odds Ratios and 95% Confidence Intervals for the Association Between Circulating 25(OH)D and Risk of Upper Gastrointestinal Cancer Overall and by Season or Sex Within the Cohort Consortium Vitamin D Pooling Project of Rarer Cancers

	Circulating 25(OH)D, nmol/L																							P_trend
	<25				25–<37.5				37.5–<50				50–<75^a			75–<100				≥100
	No. of Cases	No. of Controls	OR	95% CI	No. of Cases	No. of Controls	OR	95% CI	No. of Cases	No. of Controls	OR	95% CI	No. of Cases	No. of Controls	OR	No. of Cases	No. of Controls	OR	95% CI	No. of Cases	No. of Controls	OR	95% CI
All subjects^b	241	252			248	239			224	223			249	252		83	77			20	23
Crude			0.96	0.72, 1.28			1.04	0.80, 1.37			1.02	0.79, 1.33			1.0			1.09	0.76, 1.57			0.88	0.45, 1.70	0.79
Multivariate adjusted			0.90	0.65, 1.24			1.03	0.76, 1.39			0.92	0.69, 1.23			1.0			1.17	0.79, 1.75			0.81	0.39, 1.69	0.54
All subjects, winter^c	183	202			161	136			105	110			83	80		24	25			4	3
Crude			0.89	0.60, 1.32			1.16	0.78, 1.74			0.93	0.62, 1.42			1.0			0.96	0.50, 1.84			1.20	0.24, 5.94	0.71
Multivariate adjusted			0.87	0.57, 1.31			1.13	0.74, 1.72			0.89	0.58, 1.38			1.0			0.82	0.41, 1.65			0.97	0.17, 5.43	0.81
All subjects, summer^c	58	50			87	103			119	113			166	172		59	52			16	20
Crude			1.18	0.75, 1.87			0.86	0.60, 1.25			1.07	0.76, 1.51			1.0			1.17	0.76, 1.81			0.83	0.41, 1.69	1.00
Multivariate adjusted			0.90	0.55, 1.46			0.79	0.53, 1.17			0.98	0.68, 1.40			1.0			1.30	0.82, 2.06			0.83	0.40, 1.74	0.23
Men^b	177	190			176	152			149	155			190	193		63	65			20	21
Crude			0.95	0.68, 1.33			1.19	0.86, 1.63			0.99	0.72, 1.34			1.0			0.97	0.64, 1.47			0.95	0.48, 1.89	0.85
Multivariate adjusted			0.89	0.61, 1.31			1.23	0.85, 1.76			0.87	0.62, 1.24			1.0			1.03	0.65, 1.64			0.88	0.41, 1.89	0.97
Women^b	64	62			72	87			75	68			59	59		20	12			0	2
Crude			0.98	0.55, 1.73			0.79	0.46, 1.34			1.10	0.66, 1.83			1.0			1.83	0.81, 4.14					0.39
Multivariate adjusted			0.88	0.47, 1.65			0.78	0.44, 1.38			0.96	0.56, 1.67			1.0			1.79	0.74, 4.33					0.34

Abbreviations: CI, confidence interval; 25(OH)D, 25-hydroxyvitamin D; OR, odds ratio.

Reference category.

Conditional logistic regression models were matched on cohort, race, sex, and date of blood draw without or with further adjustment for alcohol drinking, smoking, education, and history of gastric surgery.

Unconditional logistic regression models were adjusted for the matching factors cohort, race, sex, and date of blood draw without or with further adjustment for alcohol drinking, smoking, education, and history of gastric surgery.