Table 1.
Baseline Characteristics of the Renin-angiotensin System Study Cohort.
|
N=257 |
||
|---|---|---|
| Variable | Mean or % | SD |
| Age (years) | 30.2 | 9.6 |
| Sex (% male) | 48 | |
| Diabetes duration (years) | 11.3 | 4.7 |
| Glycosylated hemoglobin(%) | 8.5 | 1.6 |
| Body mass (kg/m2) | 25.8 | 3.7 |
| Systolic blood pressure (mmHg) | 120 | 12 |
| Diastolic blood pressure (mmHg) | 70 | 8 |
| Mean arterial blood pressure (mmHg) | 87 | 9 |
| Serum creatinine (mg/dl) | 0.81 | 0.14 |
| Glomerular filtration rate (ml • min • 1.73 m2) | 129 | 20 |
| Albumin excretion rate (μg/min) | 6.4 | 5.9 |
| Mesangial fractional volume/glomerulusa | 0.21 | 0.04 |
| Mesangial matrix fractional volume/glomerulusa | 0.11 | 0.03 |
| Mesangial cell fractional volume/glomerulusa | 0.072 | 0.020 |
| Glomerular basement membrane widtha (nm) | 476 | 92 |
| Peripheral GBMb surface density/glomerulusa | 0.13 | 0.02 |
| Volume fractions of cortex which was interstitiumb | 0.110 | 0.036 |
| Volume fraction cortical tubules per total tubules which were atrophicc | 0.004 | 0.019 |
| Index of arteriolar hyalinosisd | 1.1 | 0.2 |
| Glomerulopathy indexa | 58.1 | 10.6 |
| Diabetic Retinopathy Severity | ||
| None, % | 34.6 | |
| Mild, % | 55.3 | |
| Moderate to Severe, % | 10.2 | |
| Central retinal arteriole equivalent (μm) | 159 | 13 |
| Central retinal venule equivalent (μm) | 228 | 22 |
GBM: glomerular basement membrane.
a
N = 256
b
N = 223
c
N = 210
d
N = 231