Table 2.

Correlations of Central Retinal Arteriole Equivalent (CRAE) and Central Retinal Venule Equivalent (CRVE) at Baseline with Change in Diabetic Nephropathy Measures and Incident Abnormal Values over 5-year of Follow-up.

		CRAE		CRVE
	N at riska	rb	P	rb	P
Change in:
Glomerular filtration rate	236	−0.03	0.61	0.00	0.98
Albumin excretion rate	234	0.00	0.96	0.01	0.93
Mesangial fractional volume/glomerulus	234	0.08	0.20	0.07	0.28
Mesangial matrix fractional volume/glomerulus	234	0.12	0.07	0.13	0.05
Mesangial cell fractional volume/glomerulus	234	−0.02	0.71	−0.00	0.99
Glomerular basement membrane (GBM) width (nm)	234	0.11	0.08	0.10	0.12
Peripheral GBM surface density/glomerulus	234	−0.11	0.09	−0.16	0.02
Volume fraction of cortex which was interstitium	183	−0.03	0.64	0.08	0.26
Volume fraction cortical tubules per total tubules which were atrophic	165	−0.09	0.23	−0.011	0.16
Glomerulopathy index	234	0.14	0.03	0.13	0.04
Incident abnormal:
Mesangial fractional volume/glomerulus (n = 30)	206	−0.05	0.50	−0.04	0.61
Mesangial matrix fractional volume/glomerulus (n = 43)	165	0.11	0.14	0.12	0.13
Mesangial cell fractional volume/glomerulus (n = 20)	216	0.02	0.74	−0.00	0.95
GBM width (n = 27)	93	0.09	0.41	0.10	0.35
Peripheral GBM surface density/glomerulus (n = 61)	206	0.08	0.25	0.14	0.05
Glomerulopathy index (n = 27)	86	0.23	0.04	0.22	0.04

^aNumbers at risk vary due to gradable measurement of nephropathy measures and those with prevalent abnormal values at baseline.

^br = Pearson correlation for continuous measures (top 9 rows) and Spearman correlation for categorical measures (bottom 6 rows).