. Author manuscript; available in PMC: 2011 Aug 1.

Published in final edited form as: Diabetologia. 2010 May 1;53(8):1638–1646. doi: 10.1007/s00125-010-1763-3

Table 4.

Relation of Central Retinal Arteriole Equivalent and Central Retinal Venule Equivalent at Baseline to 5-year Incidence of Renal Abnormality Models.

Incident Variable	Independent Variable
	Central retinal arteriole equivalent per SD				Central retinal venule equivalent per SD
	Duration adjusted		Multivariate adjusted^a		Duration adjusted		Multivariate adjusted^a
	OR (95% CI)^b	P	OR (95% CI) ^b	P	OR (95% CI)^b	P	OR (95% CI)^b	P
Abnormal mesangial fractional volume/glomerulus	0.86 (0.58, 1.27)	0.45			0.88 (0.59, 1.31)	0.53
Abnormal mesangial matrix fractional volume/glomerulus	1.38 (0.96, 1.98)	0.08			1.30 (0.92, 1.85)	0.14
Abnormal mesangial cell fractional volume	1.03 (0.64, 1.64)	0.91			1.00 (0.63, 1.58)	0.99

Abnormal glomerular basement membrane (GBM) width	1.36 (0.85, 2.19)	0.20			1.38 (0.85, 2.23)	0.19
Abnormal peripheral GBM surface density/glomerulus	1.23 (0.90, 1.67)	0.19			1.37 (1.01, 1.85)	0.04	1.07 (0.76, 1.50)	0.70
Abnormal glomerulopathy index	1.93 (1.16, 3.20)	0.01	1.48 (0.76, 2.86)	0.25	1.81 (1.07, 3.05)	0.03	1.25 (0.64, 2.45)	0.51

Multivariate adjustment:

Abnormal peripheral GBM surface density/glomerulus: diabetes duration, glycosylated hemoglobin, study site.

Abnormal glomerulopathy index: diabetes duration, glycosylated hemoglobin, age.

OR (95% CI) from logistic regression model.