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Proposed model for chromosome segregation. (A) Upon replication of the origin region, Soj/ParA (not shown) helps re-position the origins by acting on Spo0J/ParB (purple circle) bound to the parS sites. (B) ParB-parS recruits the SMC condensation complex (yellow circle) to the re-positioned origins. (C) SMC organizes this region and promotes efficient chromosome segregation through compaction of the DNA as it emerges from the replisome (grey circle) located at mid-cell.
