Figure 2.

Receptor-meditated uptake of ⁸⁶Y-CHX-A″-DTPA-panitumumab in selected organs of female athymic (NCr) nu/nu mice bearing human colorectal carcinoma LS-174T (A), human prostate carcinoma PC-3 (B) and human epidermoid carcinoma A431 tumor xenografts (C). Biodistribution data were obtained at 3 d after injection. All values are expressed as % ID/g. Data represent the mean value ± SEM from at least three determinations.

^*Receptor blocking studies were performed by co-injecting 0.1 mg panitumumab with the radiotracer.