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. Author manuscript; available in PMC: 2011 Mar 14.
Published in final edited form as: Structure. 2010 Mar 14;18(4):436–448. doi: 10.1016/j.str.2010.01.013

Figure 2. Crystal Structure of the Aer2 N-Terminal Domain Contains Three Successive and Interwoven HAMP Domains.

Figure 2

Ribbon presentation of the Aer2 (1-172) dimer with HAMP1 (AS1: light blue, AS2: blue), HAMP2 (AS1: orange, AS2: yellow), and HAMP3 (AS1: light purple, AS2: purple). HAMP2/3 forms a concatenated structure. AS2 of HAMP1 is contiguous with AS1 of HAMP2 and AS2 of HAMP2 is contiguous with AS1 of HAMP3. HAMP3 is rotated roughly 90 relative to HAMP1 and HAMP2.