Table 1.
Study enrolment and follow-up of fetuses according to ventriculomegaly (VM) group
All | Group 1 Normal | Group 2 Isolated VM, 10–12 mm | Group 3 Isolated VM, >12 mm | Group 4 Other CNS findings | |
---|---|---|---|---|---|
Total | 314 | 32 | 133 | 32 | 117 |
Lost from standardized postnatal follow-up due to: | |||||
Elective termination | 52 | 0 | 7 | 5 | 40 |
Stillbirth/spontaneous pregnancy loss | 5 | 0 | 2 | 0 | 3 |
Neonatal demise | 4 | 0 | 0 | 0 | 4 |
Live birth surviving neonatal period (% of Total) | 253 (81) | 32 (100) | 124 (93) | 27 (84) | 70 (60) |
Lost from study due to postnatal exclusion* | 17 | 1 | 6 | 1 | 9 |
Available for postnatal enrollment | 236 | 31 | 118 | 26 | 61 |
Lost to follow-up or declined postnatal testing | 93 | 16 | 47 | 9 | 21 |
Postnatal neurodevelopmental testing (% of those available for postnatal enrollment) | 143 (60) | 15 (48) | 71 (61) | 17 (65) | 40 (66) |
Known outcome† (% of Total) | 221 (70) | 16 (50) | 86 (65) | 23 (72) | 96 (82) |
Data are n or n (%).
Known abnormal outcome (syndromes, conditions or karyotypes associated with well-documented developmental delays or abnormal neurological findings) but excluded because of follow-up elsewhere.
Equals total minus those lost to follow-up. CNS, central nervous system.