. Author manuscript; available in PMC: 2010 Jun 28.

Published in final edited form as: Cell. 2009 Dec 24;139(7):1255–1267. doi: 10.1016/j.cell.2009.12.018

Table 1. Network parameters of influenza and cellular protein interaction networks.

The parameters in this table quantify the numbers of interactions between a defined set of proteins (one set in each column) with the entire human interaction network (see Experimental Procedures). For example, there are 87 H1 proteins (i.e. direct interactors with the 10 PR8 viral proteins) that interact with 2768 human proteins with an average of 34.4 interactions per H₁ protein (with standard deviation of 42.9). The H₁H₂ set includes the 87 H₁ proteins and 566 H2 proteins that interact with them based on curated associations. X-H₁ consists of the direct human interactors of the viral protein X.

Network parameters	All-H₁	All-H₁H₂	PB1-H₁	PB2-H₁	PA-H₁	NP-H₁	M1-H₁	M2-H₁	NS1-H₁	NS2-H₁	HA-H₁	NA-H₁	H. Sapiens
Nodes	87	653	23	32	21	12	11	9	20	2	3	2	11624
Total edges	2768	17106	1312	1640	156	686	378	384	549	50	9	11	57206
Average Degree	34.4	30.6	60.0	55.4	8.2	57.3	37.8	48.3	32.5				9.9
Stdev Degree	42.9	43.6	50.3	49.6	7.7	36.2	40.6	48.7	47.1				19.9
Median Degree	17	15	53	47	5	59	31	32	17				4