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. Author manuscript; available in PMC: 2010 Jun 28.
Published in final edited form as: Dev Biol. 2006 Oct 24;303(1):16–28. doi: 10.1016/j.ydbio.2006.10.028

Fig. 4.

Fig. 4

Kinase activity is required for dco to suppress Hid-mediated apoptosis in the eye. Adult eyes from GMR-Gal4, GMR-hidala5 and either UAS-GFP (A), UAS-dco (B), UAS-dcoD132N (C) or UAS-dcoK38R (D). While the ATP-binding mutant dcoD132N suppresses Hid activity as well as wild-type dco, the kinase dead mutant K38R enhances the small eye phenotype. (E, F) Enhancement was also observed with a weaker GMR-hid transgene. GMR-Gal4, GMR-hid1M and either UAS-GFP (E) or UAS-dcoK38R (F). Wild type dco and dcoD132N strongly suppressed GMR-hid1M (data not shown).