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This figure shows the biochemical reactions and enzymes involved in the generation of light signals by DNA pyrosequencing (18). Each peak in the pyrograms represents a pulse of light detected in the instrument. ATP, adenosine triphosphate; ADP, adenosine diphosphate; dNDP, deoxy-nucleotidyl diphosphate; dNMP, deoxy-nucleotidyl monophosphate; PPi, pyrophosphate. Adapted from www.biotagebio.com
